Bioreactors and Fermenters for Bioprocessing

Automatic Multistage Continuous Fermenter

(Stainless Steel Bioreactor System)

The Automatic Multistage Continuous Fermenter combines scalability with integrated control. Designed specifically to simulate the microbial process scale-up, it can operate multiple fermentation stages (continuous or parallel) simultaneously, ensuring a smooth transition of processes from laboratory development to industrial production.

Key Parameters
  • Capacity:
    1. First-Stage Seed Vessel: 30L / 50L / 100L
    2. Fermentation Vessel: 300L / 500L / 1000L / 2000L
    3. Customizable range: 5L - 1000L, supports multi-stage customization
  • Vessel Material: SUS316L / SUS304 Stainless Steel
  • Surface Finish: Inner surface High-Precision Polish (Ra≤0.4); Outer surface polish (Ra≤0.6)
  • Working Volume: 30% - 75%
  • Temperature: Heating/Cooling dual control; Precision: ±0.2℃
  • pH: 0-12 (±0.01), Bi-directional Auto-Regulation (Acid/Alkali)
  • DO (Dissolved Oxygen): 0-200% (±0.1)
  • Sterilization: Fully Automatic SIP (Steam-In-Place). Includes sterilization timing, pressure holding, and independent filter sterilization
  • Pressure: 0 - 3 bar (Precision 0.01 bar), supports digital setting and automatic regulation
FZ-DS Series Multistage Fermenter (Cost-Effective)

It is a high-cost-performance series that features full automation for temperature and pressure, while flow rate is controlled manually.

Model FZ-DS Series Multistage Fermenter (Cost-Effective)
Control Functions Temperature Measure & Control Seed Vessel:
30L / 50L / 100L
Fermentation Vessel:
300L / 500L / 1000L / 2000L
PH Measure & Control
DO Measure & Control
Agitation Speed Variable Frequency
Sterilization Automatic
Pressure Measure & Control
Flow Rate Manual
Acid/Alkali Auto-Control
Foam Control Auto-Control
Feeding Peristaltic Pump
FZ-ES Series Multistage Fermenter (Advanced)

Features advanced automation capabilities, including full automatic measurement and control of flow rates and pressure, allowing for fully simulating the operation of large-scale industrial vessel operations.

Model FZ-ES Series Multistage Fermenter (Advanced)
Control Functions Temperature Measure & Control Seed Vessel:
30L / 50L / 100L
Fermentation Vessel:
300L / 500L / 1000L / 2000L
PH Measure & Control
DO Measure & Control
Agitation Speed Variable Frequency
Sterilization Automatic
Pressure Measure & Control
Flow Rate Measure & Control
Acid/Alkali Auto-Control
Foam Control Auto-Control
Feeding Peristaltic Pump
Please find below some examples of customized FZ-ES series multi-stage fully automatic fermenter that we have supplied to clients.
FZ-ES-30L-300L (2-Stage Automatic Fermenter)
FZ-ES-30L-300L (2-Stage Automatic Fermenter)
  • Seed Vessel: 30L
  • Fermentation Vessel: 300L
FZ-ES-50L-500L (2-Stage Automatic Fermenter)
FZ-ES-50L-500L (2-Stage Automatic Fermenter)
  • Seed Vessel: 50L
  • Fermentation Vessel: 500L
FZ-ES-100L-2000L (2-Stage Automatic Fermenter)
FZ-ES-100L-2000L (2-Stage Automatic Fermenter)
  • Seed Vessel: 100L
  • Fermentation Vessel: 2000L
FZ-ES-30L-50L-200L (3-Stage Automatic Fermenter)
FZ-ES-30L-50L-200L (3-Stage Automatic Fermenter)
  • Seed Vessel: 30L
  • Fermentation Vessel: 50L, 200L
FZ-ES-10L-50L-500L (3-Stage Automatic Fermenter)
FZ-ES-10L-50L-500L (3-Stage Automatic Fermenter)
  • Seed Vessel: 10L
  • Fermentation Vessel: 50L, 500L
FZ-ES-10L-100L-1000L (3-Stage Automatic Fermenter)
FZ-ES-10L-100L-1000L (3-Stage Automatic Fermenter)
  • Seed Vessel: 10L
  • Fermentation Vessel: 100L, 1000L
FZ-ES-10L-50L-100L-500L (4-Stage Automatic Fermenter)
FZ-ES-10L-50L-100L-500L (4-Stage Automatic Fermenter)
  • Seed Vessel: 10L
  • Fermentation Vessel: 50L, 100L, 500L
FZ-DS-30L-100L-300L (3-Stage Automatic Fermenter)
FZ-DS-30L-100L-300L (3-Stage Automatic Fermenter)
  • Seed Vessel: 30L
  • Fermentation Vessel: 100L, 300L
FZ-DS-10L-100L-1000L (3-Stage Automatic Fermenter)
FZ-DS-10L-100L-1000L (3-Stage Automatic Fermenter)
  • Seed Vessel: 10L
  • Fermentation Vessel: 100L, 1000L
Technical Documentation Download