Multi-Stage Industrial Bioreactor
(Stainless Steel Bioreactor System, Bioreactor Continuous Process)
Multi-Stage Industrial Bioreactors are specifically designed for large-scale microbial cultivation, ensuring high efficiency and stability through multi-stage linkage. We offer industrial fermentation vessels ranging from 1,000L to 120,000L (120KL), with custom capabilities up to 200KL, fully meeting industrial mass production requirements. Through multi-stage scale-up (e.g., 300L → 3KL → 30KL), the fermenter ensures high seed viability and sufficient inoculation volume. This effectively shortens the lag phase and minimizes the economic risk of contamination in large-scale vessels.
- Capacity: 1,000L – 200,000L (Customizable)
- Vessel Material: SUS316L / SUS304 Stainless Steel
- Surface Finish: Inner surface high-precision polish (Ra≤0.4); Outer surface polish (Ra≤0.6)
- Working Volume: 30% - 75%
- Temperature: Heating/Cooling dual control; Precision: ±0.2℃
- pH: 0-12 (±0.01), Automatic bi-directional regulation (Acid/Alkali)
- DO (Dissolved Oxygen): 0-200% (±0.1)
- Sterilization: Fully Automatic SIP (Steam-In-Place), including sterilization timing, pressure holding, and independent filter sterilization
- Pressure: 0 - 3 bar (±0.01), supports digital setting and automatic regulation
| Models | ||||
| Control Functions | Temperature | Measure & Control | Measure & Control | Measure & Control |
| PH | Measure & Control | Measure & Control | Measure & Control | |
| DO | Measure & Control | Measure & Control | Measure & Control | |
| Agitation Speed | Variable Frequency | Variable Frequency | Variable Frequency | |
| Sterilization | Automatic | Automatic | Automatic | |
| Pressure | Measure & Control | Measure & Control | Manual | |
| Flow Rate | Measure & Control | Manual | Manual | |
| Acid/Alkali | Auto-Control | Auto-Control | Auto-Control | |
| Foam Control | Auto-Control | Auto-Control | Auto-Control | |
| Feeding | Peristaltic Pump | Peristaltic Pump | Peristaltic Pump | |
Large-volume design with precise regulation of agitation, temperature, and aeration to improve yield stability.
Equipped with an automated control system and online monitoring to minimize human error. Supports continuous or semi-continuous production, significantly boosting efficiency.
Structures comply with industrial sanitary standards, facilitating easy cleaning and reducing contamination risks.
This enables real-time regulation of all fermentation parameters, with all data curves being recorded. This minimizes variations caused by manual operation, while facilitating the replication and comparison of experimental conditions.
Features a proprietary tubular heat exchanger system for rapid heat dissipation.
Equipped with a proprietary gas distributor to maximize Dissolved Oxygen (DO) levels.
Below is a custom-built 3-stage Industrial Bioreactor for a biopharmaceutical client. The client selected the FZ-ES-300L → 3KL → 30KL fermenter, providing a high-activity, stable, and cost-effective solution for large-scale fermentation.
